First, you have to realize that Category A substances are infectious substances that are transported in a structure that, when presented to them happens, is capable of causing permanent disability, dangerous or fatal disease, in any case, healthy humans or animals. 

• Infectious substances that would be sent in this Category include: 
• Coccidioides immitis (societies as it were). 
• Francisella tularensis (societies as it were). 
• Hepatitis B virus (HepB) (societies as it were). 
• Herpes B virus (societies as it were). 
• Human immunodeficiency virus (HIV) (societies as it were). 
• Rabies virus (societies as it were). 

Human blood also falls into Category A; this classification requires professional judgment and is based on a patient’s known medical history, indications, individual circumstances of the source, and endemic conditions. Like blood that has been drawn from a seriously sick patient whose travel history and potential presentations place him/her in danger of contamination with viruses, for example, Ebola, Lassa, Rift Valley Fever, and so forth, would be dispatched as a Category A substance. 

According to the University of Washington, Biological Substances Category B are substances that are infectious substances that don’t meet the criteria for consideration in Category A. 

Category b shipping incorporates: 

• Adenovirus (replication equipped). 
• E. coli: Non-K-12 derivatives that require biosafety level 2 containment. 
• Recombinant viral vectors (replication inadequate), including AAV, Adenovirus, FIV, HIV. 

Human blood could also fall into Category B; this classification requires professional judgment and is based on a patient’s known medical history, manifestations, circumstances of the source, and endemic conditions. If the blood has been drawn from a HepB/HIV-positive patient, it would be classified as Category B (just CULTURES of HepB/HIV are Category A). 

Category b shipping must show the name “Biological Substance, Category B” and UN 3373. Packaging Category B infectious substances must be significantly increased, packaged and compliant with IATA Packing Instruction. 

At the primary example receptacle, you should place each sample in a 95 kPa-tried example receptacle that doesn’t allow fluids or solids to leak out. Leave an air space, receptacles containing liquids, for example, pee containers. The maximum quantity for a primary receptacle is 500 ml or 500 g. 

Place the primary example receptacle inside another 95 kPa-tried container (either flexible or inflexible) that is also leak-evidence and filter confirmation. If more than one primary case is being placed in the secondary packaging, use bubble wrap or other material for padding between the containers. 

If secondary packaging isn’t pre-labeled, add an international biohazard label to the secondary packaging. 

Place the secondary packaging(s) inside an unbending external packaging. If you are reusing a box, please eliminate or obscure any old labels from past employment. 

The external packaging must be large enough to hold the secondary packaging(s) and accurately display the necessary external packaging markings and transport reports, for example, the shipping label. The surface of the outer packaging must be four × 4 inches. 

Incorporate the name and telephone number (counting area code) of a crisis contact from your facility on the external packaging. This information can be given as part of the return address or as a separate package notation. 

This designated crisis contact individual accepts responsibility to be available during the regular business hours of your facility to give accident mitigation information in case the package is damaged or the example leaks during transit. 

Remember, the total maximum quantity for an external package containing Category B infectious substances is 4 L (fluids) or 4 kg (solids).